About Conolidine alkaloid for chronic pain
Most a short while ago, it's been discovered that conolidine and the above derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in identical regions as classical opioid receptors, it binds to the big selection of endogenous opioids. Not like most opioid receptors, this receptor functions being a scavenger and does not activate